Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.63 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969024 | 0.87 | S1PR1 (0.71) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1968276 | 0.85 | S1PR1 (0.72) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1965196 | 0.79 | S1PR1 (0.69) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1965815 | 0.78 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2298013 | 0.77 | S1PR1 (0.58) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2299282 | 0.76 | S1PR1 (0.57) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL3630847 | 0.74 | S1PR1 (0.79) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1966625 | 0.73 | S1PR1 (0.81) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1965564 | 0.72 | S1PR1 (1.00) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1965472 | 0.71 | S1PR1 (0.81) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | claimed |