Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942525 | 0.88 | POLB (0.66) | POLBTP53MAPTKDM1AMAOA | |
| Hydrochloric Acid SCHEMBL3942522 | 0.87 | POLB (0.64) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL8867533 | 0.87 | POLB (0.64) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL3968088 | 0.87 | POLB (0.64) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL1707562 | 0.86 | POLB (0.68) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL21054940 | 0.85 | POLB (0.62) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL590420 | 0.85 | POLB (0.62) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL10598558 | 0.84 | POLB (0.69) | POLBTP53MAPTKDM1AMAOA | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.84 | POLB (0.78) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL10595799 | 0.84 | POLB (0.73) | POLBTP53MAPTKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954316-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-03-23 | — | — | US | disclosed |
| WO-2017207564-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-12-07 | — | — | WO | disclosed |