Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15123572 | 0.99 | EPHX2 (0.58) | EPHX2KMT2ANPC1RECQLRAB9A | |
| SCHEMBL23212115 | 0.90 | EPHX2 (0.65) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL31607197 | 0.90 | EPHX2 (0.65) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL30567065 | 0.89 | EPHX2 (0.60) | EPHX2KMT2ANPC1RECQLRAB9A | |
| SCHEMBL728117 | 0.87 | EPHX2 (0.64) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL13852689 | 0.86 | EPHX2 (0.58) | EPHX2KMT2ANPC1RECQLRAB9A | |
| SCHEMBL2465503 | 0.86 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL27952559 | 0.85 | EPHX2 (0.59) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL15160758 | 0.85 | EPHX2 (0.62) | EPHX2KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2465375 | 0.85 | EPHX2 (0.62) | EPHX2KMT2AFABP7FABP5CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954316-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-03-23 | — | — | US | disclosed |
| WO-2017207564-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-12-07 | — | — | WO | disclosed |