Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | MC5R | P33032 | 2/20 | 0.66 |
| ▸ | MC3R | P41968 | 2/20 | 0.66 |
| ▸ | MC1R | Q01726 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | AANAT | Q16613 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689740 | 0.94 | BCHE (0.64) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL22222026 | 0.94 | BCHE (0.72) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL22221910 | 0.94 | BCHE (0.76) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL11934860 | 0.93 | BCHE (0.60) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL13438730 | 0.93 | BCHE (0.60) | BCHEMC5RMC3RMC1RHTR2A | |
| Hydrochloric Acid SCHEMBL23722025 | 0.93 | BCHE (0.74) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL11471892 | 0.93 | BCHE (0.79) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL8240955 | 0.92 | SLC6A4 (0.69) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL20689744 | 0.91 | MC5R (0.66) | BCHEMC5RMC3RMC1RHTR2A | |
| SCHEMBL17232881 | 0.84 | MC5R (0.83) | BCHEMC5RMC3RMC1RHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| EP-2334643-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | Actelion Pharmaceuticals Ltd. (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | BCHE 867/4885MC5R 116/4885MC3R 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.