Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 16/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | CDK11B | P21127 | 1/20 | 0.55 |
| ▸ | CCNC | P24863 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.55 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873192 | 0.90 | FLT3 (0.69) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL23047306 | 0.85 | FLT3 (0.54) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL20873224 | 0.83 | FLT3 (0.71) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL19683747 | 0.83 | FLT3 (0.64) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL19683869 | 0.82 | FLT3 (0.69) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL19683623 | 0.80 | FLT3 (0.74) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL19683707 | 0.79 | FLT3 (0.65) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL23047290 | 0.79 | FLT3 (0.55) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL19683780 | 0.79 | FLT3 (0.71) | FLT3CSF1RLCKRETPDGFRB | |
| SCHEMBL19683833 | 0.78 | FLT3 (0.53) | FLT3CSF1RLCKRETPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |