Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19656241 | 0.90 | ELANE (0.52) | ELANECTSKMEN1KMT2ACYP3A4 | |
| SCHEMBL19656274 | 0.87 | ELANE (0.49) | ELANECTSKMEN1KMT2ACYP3A4 | |
| SCHEMBL19656260 | 0.86 | ELANE (0.49) | ELANECTSKMEN1KMT2ACYP3A4 | |
| SCHEMBL19640000 | 0.85 | ELANE (0.56) | ELANECTSKMEN1KMT2ACYP3A4 | |
| SCHEMBL19656244 | 0.84 | ELANE (0.47) | ELANECTSKMEN1KMT2ACYP2C9 | |
| SCHEMBL19656262 | 0.84 | ELANE (0.49) | ELANECTSKMEN1KMT2A | |
| SCHEMBL21796105 | 0.84 | ELANE (0.49) | ELANECTSKMEN1KMT2A | |
| Benzene SCHEMBL19639971 | 0.83 | ELANE (0.48) | ELANECTSKMEN1KMT2A | |
| SCHEMBL19656257 | 0.83 | ELANE (0.47) | ELANECTSKMEN1KMT2A | |
| SCHEMBL19656245 | 0.83 | ELANE (0.48) | ELANEMEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207432-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |