SCHEMBL19684409

SCHEMBL19684409

Cn1c(-c2ccnn2-c2ccc(C#N)cc2)c(C(=O)NC2CCC(CBr)CC2)c(=O)n1-c1cccc(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 18/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19651229 1.00 ELANE (0.49) ELANE
SCHEMBL19656243 0.94 ELANE (0.50) ELANE
SCHEMBL21796143 0.92 ELANE (0.48) ELANE
Benzene SCHEMBL19640013 0.91 ELANE (0.48) ELANE
SCHEMBL19656261 0.91 ELANE (0.50) ELANE
SCHEMBL19651226 0.91 ELANE (0.52) ELANE
SCHEMBL21796109 0.90 ELANE (0.48) ELANE
SCHEMBL19651228 0.90 ELANE (0.48) ELANE
Bromide SCHEMBL19639993 0.90 ELANE (0.48) ELANE
SCHEMBL21796077 0.89 ELANE (0.48) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017207432-A1 NOVEL COMPOUNDS CHIESI FARMACEUTICI S.P.A. (IT) 2017-12-07 WO disclosed