Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 18/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12059994 | 1.00 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL1968539 | 1.00 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL1965171 | 0.87 | CHRNA7 (0.67) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL15199683 | 0.85 | CHRNA7 (0.62) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL2790338 | 0.84 | CHRNA7 (0.71) | CHRNA7HTR3ADYRK1A | |
| SCHEMBL2791345 | 0.84 | CHRNA7 (0.71) | CHRNA7HTR3ADYRK1A | |
| Formic Acid SCHEMBL1970233 | 0.84 | CHRNA7 (0.63) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL15199690 | 0.84 | CHRNA7 (0.58) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL12044785 | 0.83 | CHRNA7 (0.45) | CHRNA7HTR3A | |
| SCHEMBL1963360 | 0.83 | CHRNA7 (0.45) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |