Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686185 | 0.85 | SCN4A (0.47) | HTR1DHTR1BSCN4ACYP1A2KMT2A | |
| SCHEMBL19668460 | 0.83 | HTR1B (0.46) | HTR1DHTR1BSCN4ACYP1A2CYP3A4 | |
| SCHEMBL21315610 | 0.82 | SCN4A (0.43) | HTR1DHTR1BSCN4ACYP1A2KMT2A | |
| SCHEMBL19668711 | 0.81 | SCN8A (0.44) | HTR1DHTR1BSCN4AALDH1A1MAPT | |
| SCHEMBL19668715 | 0.81 | HTR1B (0.47) | HTR1DHTR1BSCN4ACYP1A2CYP3A4 | |
| SCHEMBL19668641 | 0.78 | SCN4A (0.79) | HTR1BSCN4AALOX15MAPTL3MBTL1 | |
| SCHEMBL19668704 | 0.78 | SCN4A (0.51) | HTR1BSCN4ACYP1A2KMT2ALMNA | |
| SCHEMBL7700605 | 0.78 | HTR1B (0.56) | HTR1DHTR1BKMT2ALMNAALDH1A1 | |
| Methyl Alcohol SCHEMBL28310472 | 0.74 | SCN4A (0.47) | HTR1BSCN4ACYP1A2KMT2ALMNA | |
| SCHEMBL19121724 | 0.73 | HTR1B (0.53) | HTR1BSCN4ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492325-B2 | Compounds as inhibitors of sodium channels | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2022-11-08 | — | — | US | disclosed |
| US-20190270696-A1 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2019-09-05 | — | — | US | disclosed |
| US-20190270696-A1 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2019-09-05 | — | — | US | disclosed |
| WO-2017210371-A2 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270696-A1 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | SCN1B, CACNA1E, SCN2B | HTR1D 347/4885HTR1B 478/4885SCN4A 48/4885 |
| US-11492325-B2 | Compounds as inhibitors of sodium channels | SCN1B, CACNA1E, SCN2B | HTR1D 347/4885HTR1B 478/4885SCN4A 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.