Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 16/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686321 | 0.83 | IDH1 (0.47) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL19687198 | 0.82 | IDH1 (0.47) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL19686340 | 0.82 | IDH1 (0.47) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL19686338 | 0.82 | IDH1 (0.51) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL19686520 | 0.81 | IDH1 (0.46) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL19686317 | 0.78 | IDH1 (0.69) | IDH1IDH2 | |
| SCHEMBL20399597 | 0.77 | IDH1 (0.44) | IDH1IDH2 | |
| SCHEMBL31127045 | 0.77 | IDH1 (0.46) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL21143683 | 0.77 | IDH1 (0.46) | IDH1IDH2LMNAMEN1KMT2A | |
| SCHEMBL19687389 | 0.76 | IDH1 (0.57) | IDH1IDH2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |