Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 6/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 4/20 | 0.34 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.34 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686678 | 0.88 | IDH1 (0.37) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19687015 | 0.86 | IDH1 (0.39) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19686677 | 0.83 | EIF2AK4 (0.34) | HRH4IDH1LRRK2SMO | |
| SCHEMBL19686682 | 0.83 | EIF2AK4 (0.34) | HRH4IDH1LRRK2SMO | |
| SCHEMBL19686675 | 0.83 | EIF2AK4 (0.34) | HRH4IDH1LRRK2SMO | |
| SCHEMBL21165860 | 0.83 | IDH1 (0.36) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21165821 | 0.83 | HRH4 (0.36) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21143679 | 0.76 | IDH1 (0.45) | IDH1MAPK8MAPK9MAP3K10LRRK2 | |
| SCHEMBL31127046 | 0.76 | IDH1 (0.45) | IDH1MAPK8MAPK9MAP3K10LRRK2 | |
| SCHEMBL19686988 | 0.75 | HRH4 (0.43) | CXCR4CHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2019-07-18 | — | — | US | disclosed |
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | KCNJ11, KCNJ2, KCNJ1 | CXCR4 4412/4885CHRM3 631/4885PDE4A 875/4885 |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | CXCR4 4412/4885CHRM3 631/4885PDE4A 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.