Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 17/20 | 0.44 |
| ▸ | IDH2 | P48735 | 4/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686523 | 0.80 | IDH1 (0.44) | IDH1IDH2CCNT1 | |
| SCHEMBL19686796 | 0.76 | IDH1 (0.45) | IDH1IDH2CCNT1 | |
| SCHEMBL19687512 | 0.74 | IDH1 (0.59) | IDH1IDH2 | |
| SCHEMBL21144001 | 0.74 | IDH1 (0.50) | IDH1IDH2CCNT1 | |
| SCHEMBL31127376 | 0.74 | IDH1 (0.50) | IDH1IDH2CCNT1 | |
| SCHEMBL21143615 | 0.74 | IDH1 (0.43) | IDH1IDH2CCNT1 | |
| SCHEMBL31127242 | 0.74 | IDH1 (0.43) | IDH1IDH2CCNT1 | |
| SCHEMBL21166254 | 0.72 | IDH1 (0.43) | IDH1IDH2CCNT1 | |
| SCHEMBL21143786 | 0.72 | IDH1 (0.46) | IDH1IDH2CCNT1 | |
| SCHEMBL31127234 | 0.72 | IDH1 (0.46) | IDH1IDH2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |