Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687520 | 0.84 | KCNN2 (0.37) | KCNN2KCNN3SYKALDH1A1TSHR | |
| SCHEMBL19687492 | 0.82 | KCNN2 (0.36) | KCNN2KCNN3IDH1 | |
| SCHEMBL19686334 | 0.82 | KCNN2 (0.43) | KCNN2KCNN3IDH1TSHRSMN1; SMN2 | |
| SCHEMBL19686944 | 0.79 | KCNN2 (0.45) | KCNN2KCNN3IDH1ALDH1A1TSHR | |
| SCHEMBL19686887 | 0.78 | KCNN2 (0.48) | KCNN2KCNN3SYKIDH1ALDH1A1 | |
| SCHEMBL19686952 | 0.77 | KCNN2 (0.39) | KCNN2KCNN3SYKIDH1ALDH1A1 | |
| SCHEMBL19686284 | 0.77 | KCNN2 (0.49) | KCNN2KCNN3IDH1TSHRSMN1; SMN2 | |
| SCHEMBL19687227 | 0.77 | KCNN2 (0.46) | KCNN2KCNN3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL19687280 | 0.77 | KCNN2 (0.43) | KCNN2KCNN3SYKIDH1ALDH1A1 | |
| SCHEMBL21143707 | 0.77 | KCNN2 (0.45) | KCNN2KCNN3IDH1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |