Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.47 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.42 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687421 | 0.92 | ADORA2A (0.46) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19687068 | 0.91 | KCNN2 (0.42) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19687122 | 0.90 | KCNN2 (0.42) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19686909 | 0.89 | ADORA2A (0.47) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL31127310 | 0.89 | ADORA2A (0.47) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19686526 | 0.89 | ADORA2A (0.47) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19686525 | 0.89 | ADORA2A (0.47) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19686946 | 0.85 | KCNN2 (0.48) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19687077 | 0.84 | KCNN2 (0.47) | ADORA2AADORA1KCNN2KCNN3CYP1A2 | |
| SCHEMBL19687074 | 0.83 | KCNN2 (0.46) | ADORA2AADORA1KCNN2KCNN3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |