Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164656 | 0.88 | RAF1 (0.41) | MAPTALDH1A1 | |
| SCHEMBL3607693 | 0.80 | LCK (0.42) | BRD9LCKPTPN1CA1CA2 | |
| SCHEMBL668558 | 0.80 | RAF1 (0.49) | KMT2ARXFP1 | |
| SCHEMBL4774795 | 0.79 | RAF1 (0.36) | — | |
| SCHEMBL14402928 | 0.77 | LCK (0.36) | BRD9LCKPTPN1CNR2CA1 | |
| SCHEMBL22774675 | 0.76 | LCK (0.36) | BRD9LCKMAPTMEN1ALDH1A1 | |
| SCHEMBL6192110 | 0.75 | LCK (0.38) | BRD9LCKPTPN1CA1CA2 | |
| SCHEMBL4975602 | 0.73 | PTPN1 (0.65) | PTPN1MAPTKMT2A | |
| SCHEMBL429230 | 0.71 | PTPN2 (0.57) | PTPN1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL23274072 | 0.70 | LCK (0.39) | BRD9LCKSMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018024602-A1 | 2,7-DIAZASPIRO[4.4]NONANES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-02-08 | — | — | WO | disclosed |
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |