Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15958790 | 1.00 | CYP2C19 (0.47) | CYP2C19EPHX1NAAAHTTALDH1A1 | |
| SCHEMBL15704501 | 1.00 | CYP2C19 (0.47) | CYP2C19EPHX1NAAAHTTALDH1A1 | |
| SCHEMBL15427312 | 1.00 | CYP2C19 (0.47) | CYP2C19EPHX1NAAAHTTALDH1A1 | |
| SCHEMBL14887383 | 1.00 | CYP2C19 (0.47) | CYP2C19EPHX1NAAAHTTALDH1A1 | |
| SCHEMBL23506964 | 0.85 | EPHX1 (0.52) | CYP2C19EPHX1NAAAHTTCA12 | |
| SCHEMBL19063411 | 0.85 | EPHX1 (0.52) | CYP2C19EPHX1NAAAHTTCA12 | |
| SCHEMBL93396 | 0.85 | EPHX1 (0.52) | CYP2C19EPHX1NAAAHTTCA12 | |
| SCHEMBL22540554 | 0.85 | EPHX1 (0.52) | CYP2C19EPHX1NAAAHTTCA12 | |
| SCHEMBL23018499 | 0.85 | EPHX1 (0.52) | CYP2C19EPHX1NAAAHTTCA12 | |
| SCHEMBL200090 | 0.85 | EPHX1 (0.52) | CYP2C19EPHX1NAAAHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348424-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348424-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, CLTB, BRAP | CYP2C19 4620/4885EPHX1 4311/4885NAAA 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.