Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL19639790 | 0.99 | ELANE (0.41) | ELANECETPCTSKCYP2C9 | |
| Benzene SCHEMBL19639750 | 0.92 | ELANE (0.44) | ELANECTSKCYP2C9 | |
| SCHEMBL19639804 | 0.92 | ELANE (0.45) | ELANECTSK | |
| SCHEMBL19639768 | 0.92 | ELANE (0.44) | ELANECTSK | |
| Benzene SCHEMBL19639816 | 0.91 | ELANE (0.45) | ELANECYP2C9 | |
| SCHEMBL19639796 | 0.90 | ELANE (0.46) | ELANE | |
| SCHEMBL19639756 | 0.89 | ELANE (0.41) | ELANECETPCTSKCYP2C9 | |
| SCHEMBL19639828 | 0.88 | ELANE (0.44) | ELANECTSK | |
| SCHEMBL17819289 | 0.85 | ELANE (0.47) | ELANECTSK | |
| SCHEMBL17819328 | 0.85 | ELANE (0.46) | ELANECTSKCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464269-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF A HNE RELATED DISEASE | CHIESI FARM SPA (IT) | 2020-04-01 | — | — | EP | claimed |
| WO-2017207433-A1 | HETETOCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF A DISEASE IN WHICH HNE IS IMPLICATED | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |