Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761303 | 0.84 | CYP3A4 (0.41) | TSHRCYP4F2CYP4A11CYP3A4TDP1 | |
| SCHEMBL27714241 | 0.81 | TSHR (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL28144759 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11MAPTHSD17B10LMNA | |
| SCHEMBL5915455 | 0.79 | TSHR (0.44) | TSHRCYP4F2CYP4A11CYP3A4TDP1 | |
| SCHEMBL2363793 | 0.79 | CYP3A4 (0.37) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL9236229 | 0.78 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL19105257 | 0.78 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL27195623 | 0.78 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL29220429 | 0.76 | TSHR (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL8763640 | 0.76 | TSHR (0.54) | TSHRCYP4F2CYP4A11MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334634-A1 | (METH)ACRYLATE MONOMER, POLYMER, AND COATING AGENT | Evonik Röhm GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |
| CN-101821345-A | Aqueous dispersion comprising at least one alkyd resin and at least one polymer comprising at least one (meth) acrylate segment | EVONIK ROEHM GMBH | 2010-09-01 | — | — | CN | disclosed |
| WO-2010026119-A1 | (METH)ACRYLATE MONOMER, POLYMER, AND COATING AGENT | EVONIK RÖHM GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |