Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965375 | 0.97 | S1PR1 (0.65) | S1PR1S1PR3KDM4EALDH1A1HPGD | |
| SCHEMBL2301414 | 0.96 | S1PR1 (0.67) | S1PR1S1PR3KDM4EALDH1A1HPGD | |
| SCHEMBL1968240 | 0.87 | S1PR1 (0.67) | S1PR1S1PR3KDM4EALDH1A1HPGD | |
| SCHEMBL1966495 | 0.84 | S1PR1 (0.70) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL12830873 | 0.83 | S1PR1 (0.69) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1968254 | 0.83 | S1PR1 (0.47) | S1PR1S1PR3KDM4EALDH1A1HPGD | |
| SCHEMBL1488585 | 0.81 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1489950 | 0.81 | S1PR1 (0.67) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1966814 | 0.81 | S1PR1 (0.63) | S1PR1S1PR3KDM4EALDH1A1HPGD | |
| SCHEMBL1971713 | 0.81 | S1PR1 (0.71) | S1PR1S1PR3KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | claimed |
| WO-2010043377-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2010-04-22 | — | — | WO | claimed |