Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.70 |
| ▸ | HTR3A | P46098 | 3/20 | 0.70 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.46 |
| ▸ | WNT1 | P04628 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964774 | 1.00 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3BNPC1RAB9A | |
| SCHEMBL1965143 | 1.00 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3BNPC1RAB9A | |
| SCHEMBL261375 | 0.96 | CHRNA7 (0.72) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL261046 | 0.96 | CHRNA7 (0.72) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1965004 | 0.92 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3BNPC1RAB9A | |
| SCHEMBL1963244 | 0.92 | CHRNA7 (0.70) | CHRNA7HTR3AGSK3BNPC1RAB9A | |
| SCHEMBL1963459 | 0.91 | CHRNA7 (0.66) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1963240 | 0.91 | CHRNA7 (0.66) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1965172 | 0.91 | CHRNA7 (0.69) | CHRNA7HTR3AGSK3BNPC1RAB9A | |
| SCHEMBL1967348 | 0.91 | CHRNA7 (0.69) | CHRNA7HTR3AGSK3BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |