Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.62 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.62 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19701738 | 1.00 | LPAR3 (0.62) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL19512084 | 0.98 | LPAR3 (0.60) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL9437010 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL18309262 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL2521046 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL665394 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL8976946 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL19077685 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL2523265 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL5701887 | 0.98 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355106-A1 | INTERNAL RELEASE AGENT, COMPOSITION INCLUDING INTERNAL RELEASE AGENT, AND PROCESS FOR PRODUCING A PLASTIC LENS USING SAME COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2017-12-14 | — | — | US | disclosed |