Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19711140 | 1.00 | PIK3CD (1.00) | PIK3CDABCB1PLA2G1BATG4BCYP3A4 | |
| SCHEMBL19701902 | 0.85 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL19701906 | 0.84 | PIK3CD (1.00) | PIK3CDCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL19701904 | 0.84 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL17484854 | 0.82 | PIK3CD (0.70) | PIK3CDABCB1PLA2G1BATG4BL3MBTL1 | |
| SCHEMBL17479559 | 0.82 | PIK3CD (0.70) | PIK3CDABCB1PLA2G1BATG4BL3MBTL1 | |
| SCHEMBL17478596 | 0.82 | PIK3CD (0.70) | PIK3CDABCB1PLA2G1BATG4BL3MBTL1 | |
| SCHEMBL17478595 | 0.82 | PIK3CD (0.70) | PIK3CDABCB1PLA2G1BATG4BL3MBTL1 | |
| SCHEMBL18837763 | 0.82 | PIK3CD (0.70) | PIK3CDABCB1PLA2G1BATG4BL3MBTL1 | |
| SCHEMBL19701903 | 0.81 | PIK3CD (1.00) | PIK3CDCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355707-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS | PIK3R3, JAK2, JAK3 | PIK3CD 14/4885ABCB1 998/4885PLA2G1B 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.