⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440540 | 1.00 | — | — | |
| SCHEMBL1405881 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2144603 | 0.98 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL4636135 | 0.98 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL2144598 | 0.98 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL4431863 | 0.98 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL3303102 | 0.98 | KDM4E (0.96) | — | |
| SCHEMBL5554688 | 0.93 | KDM4E (0.88) | — | |
| SCHEMBL4705489 | 0.93 | KDM4E (0.88) | — | |
| SCHEMBL29068616 | 0.91 | KDM4E (0.84) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771340-B1 | 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI SA (FR) | 2016-04-13 | — | — | EP | claimed |
| CN-103435538-B | (R) preparation method of-3-amido piperidine hydrochlorate | ASTATECH (CHENGDU) PHARMACEUTICAL CO., LTD. (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-103435538-A | (R)-3-amino piperidine hydrochloride preparation method | ASTATECH CHENGDU PHARMACEUTICAL CO LTD | 2013-12-11 | — | — | CN | claimed |
| EP-2128258-B1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | KANEKA CORP (JP) | 2013-09-11 | — | — | EP | claimed |
| US-20130150340-A1 | 6-(4-Hydroxy-phenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-06-13 | — | — | US | claimed |
| US-20130059348-A1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | KANEKA CORPORATION (JP) | 2013-03-07 | — | — | US | claimed |
| EP-2128258-A1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | Kaneka Corporation (JP) | 2009-12-02 | — | — | EP | claimed |
| CN-121378107-A | Preparation method of (R) -3-piperidine formamide with high optical purity | 四川定科制药有限公司 | 2026-01-23 | — | — | CN | disclosed |
| CN-121378107-A | Preparation method of (R) -3-piperidine formamide with high optical purity | 四川定科制药有限公司 | 2026-01-23 | — | — | CN | disclosed |
| US-20250388606-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |
| US-12398154-B2 | Azaquinazoline pan-KRas inhibitors | Mirati Therapeutics, Inc. (US) | 2025-08-26 | — | — | US | disclosed |
| US-20250145628-A1 | PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NOVO NORDISK A/S (DK) | 2025-05-08 | — | — | US | disclosed |
| US-20250034167-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2025-01-30 | — | — | US | disclosed |
| US-20100081658-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | ROCHE PALO ALTO LLC | 2010-04-01 | — | — | US | disclosed |
| EP-2128258-A1 | NOVEL AMIDASE, GENE FOR THE SAME, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDE AND OPTICALLY ACTIVE CARBOXYLIC ACID BY USING ANY ONE OF THOSE ITEMS | Kaneka Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
| EP-2123769-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF | Kaneka Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
| WO-2009106531-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2007084319-A2 | DIARYL PIPERIDINES AS CB1 MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
| EP-0719772-B1 | OPTICALLY ACTIVE IMIDAZOLIDINONE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2000-07-12 | — | — | EP | disclosed |
| EP-0719772-A1 | OPTICALLY ACTIVE IMIDAZOLIDINONE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |