SCHEMBL1970676

SCHEMBL1970676

COC(O[Si](C)(C)C)=C1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2516334 0.98
SCHEMBL1975746 0.81
SCHEMBL13210801 0.73
SCHEMBL10310660 0.73 ESR1 (0.32)
SCHEMBL1627232 0.69
SCHEMBL1627082 0.69
SCHEMBL4527855 0.65
SCHEMBL27315911 0.62 ESR1 (0.31)
SCHEMBL18594145 0.61
SCHEMBL7779055 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066303-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF NIHON NOHYAKU CO., LTD. (JP) 2025-02-27 US disclosed
EP-4458809-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2024-11-06 EP disclosed
WO-2023127806-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 日本農薬株式会社 2023-07-06 WO disclosed
WO-2023127806-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 日本農薬株式会社 2023-07-06 WO disclosed
EP-2459525-B1 ENANTIO- AND STEREO-SPECIFIC SYNTHESES OF -AMINO- - HYDROXY AMIDES MERCK SHARP & DOHME (US) 2017-03-01 EP disclosed
US-8816090-B2 Benzisoxazole derivatives PFIZER INC. (US) 2014-08-26 US disclosed
EP-1856114-B1 BENZISOXAZOLE DERIVATIVES PFIZER (US) 2014-08-20 EP disclosed
US-8680294-B2 Enantio- and stereo specific synthesis of β-amino-α-hydroxy amides MERCK SHARP & DOHME CORP. (US) 2014-03-25 US disclosed
US-8680294-B2 Enantio- and stereo specific synthesis of β-amino-α-hydroxy amides MERCK SHARP & DOHME CORP. (US) 2014-03-25 US disclosed
US-8470763-B2 Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) 2013-06-25 US disclosed
EP-1856110-A1 OXYINDOLE DERIVATIVES AS 5HT4 RECEPTOR AGONISTS Pfizer, Inc. (US) 2007-11-21 EP disclosed
WO-2007077186-A1 PDF INHIBITORS NOVARTIS AG (CH) 2007-07-12 WO disclosed
WO-2007077186-A1 PDF INHIBITORS NOVARTIS AG (CH) 2007-07-12 WO disclosed
US-20070004735-A1 Method for inhibiting the replication of herpes viruses AICURIS GMBH & CO. KG (DE) 2007-01-04 US disclosed
WO-2006090224-A1 BENZISOXAZOLE DERIVATIVES PFIZER JAPAN INC. (JP) 2006-08-31 WO disclosed
US-20060194842-A1 Oxyindole derivatives PFIZER INC. 2006-08-31 US disclosed
WO-2006090279-A1 OXYINDOLE DERIVATIVES AS 5HT4 RECEPTOR AGONISTS PFIZER JAPAN INC. (JP) 2006-08-31 WO disclosed
EP-1472229-A1 5-RING HETEROCYCLES USED AS ANTIVIRAL AGENTS Bayer HealthCare AG (DE) 2004-11-03 EP disclosed
WO-2003064394-A1 5-RING HETEROCYCLES USED AS ANTIVIRAL AGENTS BAYER HEALTHCARE AG (DE) 2003-08-07 WO disclosed
US-6121475-A Preparation of optically active β-hydroxyester derivatives and platinum-containing catalyst UBE INDUSTRIES, LTD. (JP) 2000-09-19 US disclosed