Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 7/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.46 |
| ▸ | WNT1 | P04628 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966154 | 1.00 | CHRNA7 (0.62) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1963811 | 1.00 | CHRNA7 (0.62) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL1963432 | 0.93 | CHRNA7 (0.62) | CHRNA7HTR3AGSK3B | |
| SCHEMBL1963273 | 0.93 | CHRNA7 (0.62) | CHRNA7HTR3AGSK3B | |
| Hydrochloric Acid SCHEMBL1964985 | 0.92 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3B | |
| SCHEMBL1962855 | 0.86 | CHRNA7 (0.63) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL2855652 | 0.83 | GSK3B (0.53) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL2855656 | 0.83 | GSK3B (0.53) | CHRNA7HTR3AGSK3BDYRK1AWNT1 | |
| SCHEMBL2087133 | 0.82 | GSK3B (0.57) | GSK3BDYRK1AWNT1KCNH2 | |
| SCHEMBL260465 | 0.82 | CHRNA7 (0.77) | CHRNA7HTR3AGSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |