Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 18/20 | 0.75 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.75 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.75 |
| ▸ | BID | P55957 | 3/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.75 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.75 |
| ▸ | NSD2 | O96028 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.75 |
| ▸ | ASPH | Q12797 | 1/20 | 0.75 |
| ▸ | BAD | Q92934 | 1/20 | 0.75 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.75 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.75 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.70 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701568 | 0.93 | BCL2 (0.87) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL16038376 | 0.86 | BCL2 (0.96) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL16038769 | 0.86 | BCL2 (0.96) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL31344630 | 0.86 | BCL2 (0.91) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL1701418 | 0.86 | BCL2 (0.91) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL29373366 | 0.86 | BCL2 (1.00) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL20580441 | 0.86 | BCL2 (1.00) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL25100284 | 0.86 | BCL2 (0.86) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| Venetoclax SCHEMBL523816 | 0.86 | BCL2 (1.00) | BCL2MCL1BCL2L1BIDSLC6A3 | |
| SCHEMBL1567501 | 0.86 | BCL2 (0.93) | BCL2MCL1BCL2L1BIDSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017212431-A1 | SOLID FORMS OF VENETOCLAX AND PROCESSES FOR THE PREPARATION OF VENETOCLAX | DR. REDDY’S LABORATORIES LIMITED (IN) | 2017-12-14 | — | — | WO | disclosed |