Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | MDK | P21741 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491955 | 0.90 | PDPK1 (0.36) | PDPK1MTORTNFLGALS8ALDH1A1 | |
| SCHEMBL30689829 | 0.87 | SSTR5 (0.42) | KDM4ELMNA | |
| SCHEMBL13129921 | 0.87 | PDPK1 (0.43) | PDPK1MTORALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL2804636 | 0.87 | PDPK1 (0.43) | PDPK1MTORALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL25365555 | 0.82 | PDPK1 (0.47) | PDPK1MTORTNFALDH1A1 | |
| SCHEMBL6544929 | 0.82 | PDPK1 (0.47) | PDPK1MTORTNFALDH1A1 | |
| SCHEMBL9051284 | 0.82 | PDPK1 (0.47) | PDPK1MTORTNFALDH1A1 | |
| SCHEMBL31065200 | 0.82 | PDPK1 (0.47) | PDPK1MTORTNFALDH1A1 | |
| SCHEMBL16319220 | 0.82 | PDPK1 (0.47) | PDPK1MTORTNFALDH1A1 | |
| SCHEMBL2456260 | 0.82 | PDPK1 (0.47) | PDPK1MTORTNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164521-B1 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3A AND X | PASTEUR INSTITUT (FR) | 2018-09-12 | — | — | EP | disclosed |
| EP-2369345-B1 | Glycoconjugates and their use as potential vaccines against infection by shigella flexneri | PASTEUR INSTITUT (FR) | 2014-10-01 | — | — | EP | disclosed |
| EP-2369345-A1 | Glycoconjugates and their use as potential vaccines against infection by shigella flexneri | Institut Pasteur (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-1642132-B1 | GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI | PASTEUR INSTITUT (FR) | 2011-06-22 | — | — | EP | disclosed |