SCHEMBL1971189

SCHEMBL1971189

C=C(C)C(=O)C(=C)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
ALDH1A1 P00352 1/20 0.33
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL298108 0.84
SCHEMBL27466443 0.81
SCHEMBL14870 0.77
SCHEMBL2128293 0.77 TDP1 (1.00) TDP1LMNAALOX15BLMPMP22
SCHEMBL5708652 0.77 TDP1 (1.00) TDP1LMNAALOX15BLMPMP22
SCHEMBL3840075 0.77 TDP1 (0.61) TDP1LMNAALOX15BLMPMP22
SCHEMBL1147815 0.77 TDP1 (0.61) TDP1LMNAALOX15BLMPMP22
1,1-Dichloroethene SCHEMBL28114594 0.75 TDP1 (0.80) TDP1LMNAALOX15BLMPMP22
SCHEMBL490237 0.75
Ammonia Solution, Strong SCHEMBL7618993 0.74 TDP1 (0.92) TDP1LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334413-A2 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2011-06-22 EP claimed
WO-2010027955-A2 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF NATRIX SEPARATIONS INC. (CA) 2010-03-11 WO claimed
EP-3947335-A1 INHIBITORS OF THE N-TERMINAL DOMAIN OF THE ANDROGEN RECEPTOR The Regents of the University of California (US) 2022-02-09 EP disclosed
WO-2020205470-A1 INHIBITORS OF THE N-TERMINAL DOMAIN OF THE ANDROGEN RECEPTOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-10-08 WO disclosed
CN-110325508-A The inhibitor of the N- terminal domains of androgen receptor 加利福尼亚大学董事会 2019-10-11 CN disclosed
EP-2709749-A2 LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2014-03-26 EP disclosed
WO-2012158896-A2 LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY, AND METHODS OF USE THEREOF NATRIX SEPARATIONS INC. (CA) 2012-11-22 WO disclosed
EP-2334413-A2 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2011-06-22 EP disclosed
WO-2010027955-A2 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF NATRIX SEPARATIONS INC. (CA) 2010-03-11 WO disclosed
CN-1180688-C Stable pesticide dispersions 罗姆和哈斯公司 2004-12-22 CN disclosed
CN-1197597-A Stable pesticide dispersions ROHM & HAAS (US) 1998-11-04 CN disclosed