Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118768 | 1.00 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2621882 | 1.00 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2621887 | 0.94 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2621886 | 0.91 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2632181 | 0.90 | PDPK1 (0.81) | PDPK1 | |
| SCHEMBL2621885 | 0.88 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL19723184 | 0.88 | PDPK1 (0.82) | PDPK1 | |
| SCHEMBL2621877 | 0.86 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2621880 | 0.85 | PDPK1 (1.00) | PDPK1 | |
| SCHEMBL2632092 | 0.83 | PDPK1 (0.80) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560967-B1 | Heterocyclic carboxylic acid amides as PDK1 inihibitors | BOEHRINGER INGELHEIM INT (DE) | 2017-12-20 | — | — | EP | claimed |