SCHEMBL19715609

SCHEMBL19715609

CCCCN(C)C(=O)OCc1c(-c2ccc(O[C@H]3CCC[C@H](C(=O)O)C3)cc2)nnn1C

nearest known ligand 0.77

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SLCO1B1 Q9Y6L6 8/20 0.77
▸ ABCC3 O15438 2/20 0.65
▸ ABCC4 O15439 2/20 0.65
▸ SLCO1B3 Q9NPD5 2/20 0.65
▸ ABCB11 O95342 3/20 0.61
▸ LPAR1 Q92633 5/20 0.57
▸ AGER Q15109 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ GABRA5 P31644 1/20 0.32
▸ TSPO P30536 1/20 0.32
▸ HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19715681 0.98 SLCO1B1 (0.76) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715534 0.95 SLCO1B1 (0.79) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL28710825 0.91 SLCO1B1 (0.73) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL28712498 0.91 SLCO1B1 (0.77) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715705 0.91 SLCO1B1 (0.77) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715782 0.91 SLCO1B1 (0.77) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715789 0.91 SLCO1B1 (0.77) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715707 0.91 SLCO1B1 (0.77) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715725 0.89 SLCO1B1 (0.78) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11
SCHEMBL19715863 0.89 SLCO1B1 (0.79) SLCO1B1ABCC3ABCC4SLCO1B3ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057815-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-02-20 — — US disclosed
US-20230390249-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2023-12-07 — — US disclosed
US-RE49352-E1 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2023-01-03 — — US disclosed
US-RE49352-E1 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2023-01-03 — — US disclosed
US-20220249443-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2022-08-11 — — US disclosed
CN-114601830-A Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists 百时美施贵宝公司 2022-06-10 — — CN disclosed
CN-109963843-B Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists 百时美施贵宝公司 2022-03-11 — — CN disclosed
EP-3666771-B1 LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-09-29 — — EP disclosed
EP-3666771-B1 LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-09-29 — — EP disclosed
US-20210244711-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-08-12 — — US disclosed
US-20200138789-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2020-05-07 — — US disclosed
US-20200138789-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2020-05-07 — — US disclosed
EP-3472148-B1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2020-03-11 — — EP disclosed
US-10576062-B2 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2020-03-03 — — US disclosed
US-10576062-B2 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2020-03-03 — — US disclosed
US-20180333395-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS CHENG PETER TAI WAH (US) 2018-11-22 — — US disclosed
US-10071078-B2 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2018-09-11 — — US disclosed
US-20170360759-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS SYNGENE INTERNATIONAL LIMITED (IN) 2017-12-21 — — US disclosed
US-20170360759-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS SYNGENE INTERNATIONAL LIMITED (IN) 2017-12-21 — — US disclosed
US-20170360759-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS SYNGENE INTERNATIONAL LIMITED (IN) 2017-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360759-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-20220249443-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-20210244711-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-20200138789-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-20230390249-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-10576062-B2 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-20250057815-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-20180333395-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885
US-10071078-B2 Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists LPAR3, LPAR1, LPAR2 SLCO1B1 1507/4885ABCC3 1577/4885ABCC4 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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