SCHEMBL197158

SCHEMBL197158

C[CH]OC(C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549584 0.74
SCHEMBL19451079 0.73
SCHEMBL60694 0.69
SCHEMBL273891 0.69
SCHEMBL11493641 0.69
SCHEMBL15802700 0.69
SCHEMBL15802701 0.69
SCHEMBL2147888 0.69
SCHEMBL1013528 0.67
SCHEMBL4305457 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49481-E1 Compounds for the treatment and prophylaxis of respiratory syncytial virus disease HOFFMANN-LA ROCHE INC. (US) 2023-04-04 US claimed
US-20160297768-A1 NOVEL IMIDAZOLE DERIVATIVES AND THERAPEUTIC USE THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2016-10-13 US claimed
EP-3050875-A1 NOVEL IMIDAZOLE DERIVATIVE AND THERAPEUTICAL USE THEREOF Industry-Academic Cooperation Foundation, Yonsei University (KR) 2016-08-03 EP claimed
EP-2742039-B1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE HOFFMANN LA ROCHE (CH) 2015-09-16 EP claimed
US-8871756-B2 Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease HOFFMANN-LA ROCHE INC. (US) 2014-10-28 US claimed
EP-2742039-A1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE F. Hoffmann-La Roche AG (CH) 2014-06-18 EP claimed
US-20130196974-A1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE HOFFMANN-LA ROCHE INC. 2013-08-01 US claimed
WO-2013020993-A1 COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2013-02-14 WO claimed
US-8088559-B2 Method of making a photopolymer printing plate AGFA GRAPHICS NV (BE) 2012-01-03 US claimed
EP-1952201-B1 METHOD OF MAKING A PHOTOPOLYMER PRINTING PLATE AGFA GRAPHICS NV (BE) 2011-01-12 EP claimed
WO-2006026597-A2 NOVEL COMPOSITIONS AND METHODS OF TREATMENT SMITHKLINE BEECHAM CORPORATION (US) 2006-03-09 WO claimed
US-20050187232-A1 Methods and compositions utilizing quinazolinones CYTOKINETICS, INC. 2005-08-25 US claimed
US-20040023996-A1 Methods and compositions utilizing quinazolinones CYTOKINETICS, INC. 2004-02-05 US claimed
US-6562831-B1 Inhibitors of the mitotic kinesin KSP and are useful in the treatment of cellular proliferative diseases CYTOKINETICS, INC. 2003-05-13 US claimed
US-6545004-B1 Treating cellular proliferative diseases and disorders associated with KSP kinesin activity. CYTOKINETICS, INC. 2003-04-08 US claimed
EP-1296959-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES Cytokinetics, Inc. (US) 2003-04-02 EP claimed
WO-2001030768-A9 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES CYTOKINETICS INC (US) 2002-08-15 WO claimed
EP-1226129-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES Cytokinetics, Inc. (US) 2002-07-31 EP claimed
WO-2001098278-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES CYTOKINETICS, INC. (US) 2001-12-27 WO claimed
WO-2001030768-A1 METHODS AND COMPOSITIONS UTILIZING QUINAZOLINONES CYTOKINETICS, INC. (US) 2001-05-03 WO claimed