Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456341 | 0.85 | TNKS (0.51) | TNKSDAOKMT2AALDH1A1KDM4E | |
| SCHEMBL15550780 | 0.83 | TNKS (0.51) | TNKSKMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL16657382 | 0.81 | TNKS (0.46) | TNKSDAOMAOADYRK1A | |
| SCHEMBL16456380 | 0.81 | TNKS (0.54) | TNKSDAOKMT2AALDH1A1LMNA | |
| SCHEMBL16657373 | 0.80 | TNKS (0.52) | TNKSDAOKMT2AALDH1A1LMNA | |
| SCHEMBL16657406 | 0.79 | PARP1 (0.49) | TNKSDAOKMT2AALDH1A1KDM4E | |
| SCHEMBL18425727 | 0.78 | TNKS (0.51) | TNKSDAOKMT2AALDH1A1LMNA | |
| SCHEMBL15552211 | 0.78 | MEN1 (0.52) | TNKSDAOKMT2ALMNAFEN1 | |
| SCHEMBL16455933 | 0.77 | TNKS (0.51) | TNKSDAOKMT2AALDH1A1LMNA | |
| SCHEMBL15551636 | 0.77 | CYP2C9 (0.51) | TNKSKMT2AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845321-B2 | 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-19 | — | — | US | disclosed |