SCHEMBL19720301

SCHEMBL19720301

c1ccc2cc(-c3ccc(-c4c5ccccc5c(-c5ccc6c(-c7ccc8ccccc8c7)c7ccccc7c(-c7ccc8ccccc8c7)c6c5)c5ccccc45)cc3)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.52
ESR2 Q92731 6/20 0.52
ALOX5 P09917 2/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B1 P14061 2/20 0.44
HSD17B2 P37059 2/20 0.44
GSTP1 P09211 1/20 0.42
CYP17A1 P05093 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
PDE9A O76083 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21238074 1.00 ESR1 (0.52) ESR1ESR2ALOX5CA1CA2
SCHEMBL269358 0.96 ESR1 (0.50) ESR1ESR2ALOX5CA1CA2
SCHEMBL2964464 0.96 ESR1 (0.50) ESR1ESR2ALOX5CA1CA2
SCHEMBL259152 0.94 ESR1 (0.50) ESR1ESR2ALOX5CA1CA2
SCHEMBL3460383 0.94 ESR1 (0.50) ESR1ESR2ALOX5CA1CA2
SCHEMBL29295264 0.94 ESR1 (0.47) ESR1ESR2ALOX5CA1CA2
SCHEMBL29375861 0.94 ESR1 (0.50) ESR1ESR2ALOX5CA1CA2
SCHEMBL30150716 0.94 ESR1 (0.57) ESR1ESR2ALOX5CA1CA2
SCHEMBL2089825 0.94 ESR1 (0.57) ESR1ESR2ALOX5CA1CA2
SCHEMBL28538557 0.92 ESR1 (0.49) ESR1ESR2ALOX5CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991514-B1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2017-12-20 EP disclosed