Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317176 | 0.87 | GAA (0.47) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4412312 | 0.83 | TSHR (0.45) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19937451 | 0.82 | GAA (0.39) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3630829 | 0.81 | GAA (0.43) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13552035 | 0.81 | GAA (0.43) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15672524 | 0.81 | GAA (0.39) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL316372 | 0.81 | SMN1; SMN2 (0.47) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6299625 | 0.81 | GAA (0.44) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20195373 | 0.81 | GAA (0.40) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19937354 | 0.80 | GAA (0.42) | GAAHTTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587536-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2021-03-24 | — | — | EP | disclosed |
| EP-3083883-B1 | METHOD FOR CLEANING A LIQUID CRYSTAL MIXTURE | MERCK PATENT GMBH (DE) | 2018-07-11 | — | — | EP | disclosed |
| EP-2722380-B1 | Liquid crystal medium, method for the stabilisation thereof and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |
| EP-2855630-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |