Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672479 | 0.94 | GAA (0.39) | GAAHTTCHRM2CHRM1CHRM3 | |
| SCHEMBL16790834 | 0.89 | GAA (0.36) | GAAHTTCHRM2CHRM1CHRM3 | |
| SCHEMBL19937260 | 0.88 | GAA (0.35) | GAAHTTCHRM2CHRM1CHRM3 | |
| SCHEMBL13554334 | 0.86 | GAA (0.34) | GAAHTTCHRM2CHRM1CHRM3 | |
| SCHEMBL16869880 | 0.86 | GAA (0.34) | GAAHTTCHRM2CHRM1CHRM3 | |
| SCHEMBL21675508 | 0.86 | GAA (0.37) | GAAHTTCYP2D6LMNA | |
| SCHEMBL25805960 | 0.86 | GAA (0.37) | GAAHTTCYP2D6LMNA | |
| SCHEMBL19884609 | 0.85 | GAA (0.36) | GAAHTTCYP2D6LMNA | |
| SCHEMBL13554373 | 0.81 | TSHR (0.33) | GAACHRM2CHRM1CHRM3ADRA1A | |
| SCHEMBL22538275 | 0.81 | GAA (0.37) | GAAHTTCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855630-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |