Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20882803 | 0.97 | TSHR (0.48) | TSHRSPHK1CYP2C9SPHK2THRA | |
| SCHEMBL19844224 | 0.93 | CYP2C9 (0.40) | TSHRSPHK1CYP2C9ALDH1A1LMNA | |
| SCHEMBL19721820 | 0.89 | SPHK1 (0.44) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL19722554 | 0.89 | SPHK1 (0.43) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL19722051 | 0.89 | SPHK1 (0.43) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL19721961 | 0.88 | SPHK1 (0.46) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL9480980 | 0.87 | POLB (0.51) | TSHRCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9480987 | 0.87 | POLB (0.51) | TSHRCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL19722155 | 0.87 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL19722414 | 0.87 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257839-A1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-12-20 | — | — | EP | disclosed |