Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723548 | 0.86 | DDT (0.50) | KDM4ELMNAHTTSMN1; SMN2PKM | |
| SCHEMBL17876427 | 0.85 | KDM4E (0.58) | SCDKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL1768316 | 0.85 | KDM4E (0.60) | SCDKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL17676512 | 0.85 | SMN1; SMN2 (0.53) | KDM4ELMNAHTTSMN1; SMN2PKM | |
| SCHEMBL12296304 | 0.83 | KDM4E (0.58) | KDM4ELMNAHTTSMN1; SMN2PKM | |
| SCHEMBL12296305 | 0.83 | KDM4E (0.58) | SCDKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL19723811 | 0.81 | KDM4E (0.71) | SCDKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL12295463 | 0.81 | KDM4E (0.78) | KDM4ELMNAHTTSMN1; SMN2PKM | |
| SCHEMBL12295231 | 0.80 | KDM4E (0.55) | KDM4ELMNAHTTSMN1; SMN2PKM | |
| SCHEMBL17676251 | 0.80 | SMN1; SMN2 (0.52) | KDM4ELMNAHTTSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257854-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2017-12-20 | — | — | EP | disclosed |