Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723643 | 0.88 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL19723612 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL19723644 | 0.84 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL19723611 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL19723614 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL19723780 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL19723778 | 0.79 | MAPK1 (0.46) | SMN1; SMN2ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL19723615 | 0.77 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL19723522 | 0.77 | MAPK1 (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL23029860 | 0.71 | SMN1; SMN2 (0.78) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257854-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2017-12-20 | — | — | EP | disclosed |