Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.74 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
| ▸ | CCKAR | P32238 | 3/20 | 0.45 |
| ▸ | CCKBR | P32239 | 3/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18552076 | 0.99 | GLP1R (0.75) | GLP1RLPAR3CCKARCCKBRLPAR1 | |
| SCHEMBL24891111 | 0.92 | GLP1R (0.63) | GLP1RCCKARCCKBR | |
| SCHEMBL27327227 | 0.89 | GLP1R (0.62) | GLP1RCCKARCCKBR | |
| SCHEMBL29322838 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR | |
| SCHEMBL29323009 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR | |
| SCHEMBL15360141 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR | |
| SCHEMBL24838647 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR | |
| SCHEMBL23253771 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR | |
| SCHEMBL18893454 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR | |
| SCHEMBL8258329 | 0.88 | GLP1R (0.79) | GLP1RCCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340261-B1 | AMYLIN DERIVATIVES | NOVO NORDISK AS (DK) | 2017-12-20 | — | — | EP | disclosed |