SCHEMBL19724656

SCHEMBL19724656

Cc1cccn2c(C3(NC(=O)[C@@H]4C5CNC[C@H]54)CCOCC3)ncc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 20/20 1.00
SSTR1 P30872 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19724602 1.00 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL16256038 1.00 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL16252735 0.93 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL19724577 0.93 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL19724552 0.91 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL16252732 0.91 SSTR4 (1.00) SSTR4SSTR1
SCHEMBL24057346 0.83 SSTR4 (0.71) SSTR4SSTR1
SCHEMBL17849500 0.83 SSTR4 (0.70) SSTR4SSTR1
SCHEMBL19724817 0.83 SSTR4 (0.70) SSTR4SSTR1
SCHEMBL20029302 0.82 SSTR4 (0.69) SSTR4SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997021-B1 NEW SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS CENTREXION THERAPEUTICS CORP (US) 2017-12-20 EP disclosed