Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15148040 | 1.00 | PDE9A (1.00) | PDE9A | |
| SCHEMBL15151133 | 1.00 | PDE9A (1.00) | PDE9A | |
| SCHEMBL15145103 | 1.00 | PDE9A (1.00) | PDE9A | |
| SCHEMBL15142383 | 0.91 | PDE9A (0.82) | PDE9A | |
| SCHEMBL15145601 | 0.90 | PDE9A (0.82) | PDE9A | |
| SCHEMBL15142135 | 0.89 | PDE9A (0.81) | PDE9A | |
| SCHEMBL15279480 | 0.88 | PDE9A (0.79) | PDE9A | |
| SCHEMBL878051 | 0.88 | PDE9A (0.79) | PDE9A | |
| SCHEMBL18951508 | 0.86 | PDE9A (0.82) | PDE9A | |
| SCHEMBL9933035 | 0.85 | PDE9A (0.73) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3178820-B1 | PDE9- INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H LUNDBECK AS (DK) | 2017-12-20 | — | — | EP | disclosed |