Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725030 | 1.00 | PDE9A (0.86) | PDE9A | |
| SCHEMBL15142255 | 1.00 | PDE9A (0.86) | PDE9A | |
| SCHEMBL877874 | 1.00 | PDE9A (0.86) | PDE9A | |
| SCHEMBL15142693 | 1.00 | PDE9A (0.86) | PDE9A | |
| SCHEMBL18951482 | 1.00 | PDE9A (0.86) | PDE9A | |
| SCHEMBL16886065 | 0.93 | PDE9A (0.86) | PDE9A | |
| SCHEMBL15142157 | 0.92 | PDE9A (1.00) | PDE9A | |
| SCHEMBL15145295 | 0.92 | PDE9A (1.00) | PDE9A | |
| SCHEMBL15279580 | 0.92 | PDE9A (0.86) | PDE9A | |
| SCHEMBL15279525 | 0.92 | PDE9A (0.88) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3178820-B1 | PDE9- INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H LUNDBECK AS (DK) | 2017-12-20 | — | — | EP | disclosed |