SCHEMBL19726232

SCHEMBL19726232

CC1(C)c2ccccc2-c2ccc(N(c3ccccc3)c3ccc(N(c4ccccc4)c4ccc(N(c5ccccc5)c5ccc6c(c5)C(C)(C)c5ccccc5-6)cc4)cc3)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 11/20 0.46
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MLNR O43193 1/20 0.37
NR1I2 O75469 1/20 0.37
CHRM2 P08172 1/20 0.37
ADRB1 P08588 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
CHRM1 P11229 1/20 0.37
DRD2 P14416 1/20 0.37
ADRA2B P18089 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17014867 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL29512070 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL16200615 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL1753495 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL3793714 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL30838743 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL1338609 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL14340229 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL22000499 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E
SCHEMBL10029831 1.00 PDK2 (0.46) PDK2ALDH1A1L3MBTL1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227934-B1 ORGANIC LIGHT-EMITTING DEVICE CAMBRIDGE DISPLAY TECH LTD (GB) 2023-08-02 EP disclosed
US-11024818-B2 Organic light-emitting device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-06-01 US disclosed
US-20170365805-A1 ORGANIC LIGHT-EMITTING DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-12-21 US disclosed
US-20170365805-A1 ORGANIC LIGHT-EMITTING DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-12-21 US disclosed