Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 6/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728604 | 0.91 | KDM4E (0.41) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19728835 | 0.90 | TOP1 (0.43) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19728605 | 0.90 | TOP2A (0.42) | TOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL19729400 | 0.85 | KDM4E (0.45) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19728717 | 0.84 | STAT3 (0.38) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19728735 | 0.84 | STAT3 (0.38) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19729220 | 0.83 | KDM4E (0.42) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19729474 | 0.83 | STAT3 (0.40) | KDM4EHPGDCYP2C19STAT3ADRB2 | |
| SCHEMBL19728621 | 0.83 | TOP1 (0.34) | KDM4EHPGDCYP2C19STAT3TOP2A | |
| SCHEMBL21341272 | 0.83 | KCNH2 (0.47) | TOP2ATOP2BTOP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017217441-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | 湧永製薬株式会社 | 2017-12-21 | — | — | WO | disclosed |