Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578466 | 0.87 | GAA (0.48) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL19728828 | 0.81 | GAA (0.42) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL8111865 | 0.80 | GAA (0.48) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL1186761 | 0.78 | GAA (0.54) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL4671913 | 0.77 | MAPT (0.42) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL5704377 | 0.76 | GAA (0.47) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL7011293 | 0.75 | GAA (0.42) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL19728376 | 0.75 | GAA (0.42) | GAAMGAMSIMGAM2MAPT | |
| Acetic Acid SCHEMBL8871374 | 0.73 | GAA (0.48) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL1349347 | 0.72 | MGAM (0.47) | GAAMGAMSIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017217441-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | 湧永製薬株式会社 | 2017-12-21 | — | — | WO | disclosed |