SCHEMBL19729348 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	STAT3	P40763	3/20	0.40

▸	KDM4E	B2RXH2	3/20	0.36

▸	HPGD	P15428	3/20	0.36

▸	ALDH1A1	P00352	2/20	0.36

▸	HSD17B10	Q99714	2/20	0.36

▸	KMT2A	Q03164	2/20	0.35

▸	CYP2C19	P33261	1/20	0.35

▸	KCNH2	Q12809	1/20	0.34

▸	TOP2A	P11388	6/20	0.33

▸	TOP1	P11387	5/20	0.33

▸	HTT	P42858	1/20	0.33

▸	ADRB2	P07550	1/20	0.33

▸	TOP2B	Q02880	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19729066	0.93	STAT3 (0.38)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19729304	0.91	STAT3 (0.40)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19729349	0.91	STAT3 (0.40)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19728348	0.88	TOP2A (0.46)	ALDH1A1TOP2ATOP1TOP2B
SCHEMBL19729059	0.87	STAT3 (0.47)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19728717	0.86	STAT3 (0.38)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19728735	0.86	STAT3 (0.38)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19729071	0.84	STAT3 (0.38)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19729372	0.84	STAT3 (0.38)	STAT3KDM4EHPGDALDH1A1HSD17B10
SCHEMBL19728798	0.83	STAT3 (0.55)	STAT3KDM4EHPGDALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017217441-A1	NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF	湧永製薬株式会社	2017-12-21	—	—	WO	disclosed