SCHEMBL19731174

SCHEMBL19731174

Cc1ccc2ccccc2c1/C=C\C=N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.47
TSHR P16473 4/20 0.47
CYP1A2 P05177 4/20 0.47
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
ALDH1A1 P00352 4/20 0.41
CHAT P28329 1/20 0.40
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 4/20 0.37
ERN1 O75460 1/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25464150 0.82 CYP2A6 (0.47) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL16784687 0.81 CYP2A6 (0.54) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL22107896 0.79 CYP2A6 (0.52) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL512629 0.78 CYP2A6 (0.50) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL299445 0.78 CYP2A6 (0.50) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL8012260 0.77 CYP2A6 (0.58) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL9442847 0.76 CYP2A6 (0.48) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL16327005 0.75 CYP2A6 (0.47) CYP2A6TSHRCYP1A2ALDH1A1CHAT
SCHEMBL821212 0.75 TSHR (0.56) CYP2A6TSHRCYP1A2GRIN2DGRIN3B
SCHEMBL17410854 0.74 CYP2A6 (0.36) CYP2A6TSHRCYP1A2ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651388-B2 Compositions comprising at least one polymer and at least one metal complex and to electroluminescent devices containing said compositions MERCK PATENT GMBH (DE) 2020-05-12 US disclosed
US-20170365786-A1 COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE METAL COMPLEX AND TO ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS MERCK PATENT GMBH (DE) 2017-12-21 US disclosed