Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAS1 | P04201 | 1/20 | 0.73 |
| ▸ | AGTR2 | P50052 | 11/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15045765 | 0.84 | MAS1 (1.00) | MAS1AGTR2 | |
| SCHEMBL1334134 | 0.82 | MAS1 (0.74) | MAS1AGTR2 | |
| SCHEMBL24019097 | 0.82 | MAS1 (0.69) | MAS1AGTR2 | |
| SCHEMBL3975878 | 0.82 | MAS1 (0.73) | MAS1AGTR2 | |
| SCHEMBL29701254 | 0.82 | MAS1 (0.73) | MAS1AGTR2 | |
| SCHEMBL18768098 | 0.80 | MAS1 (0.87) | MAS1AGTR2 | |
| SCHEMBL24019101 | 0.79 | MAS1 (0.85) | MAS1AGTR2 | |
| Tromethamine SCHEMBL3912101 | 0.79 | MAS1 (0.69) | MAS1AGTR2 | |
| SCHEMBL24637550 | 0.79 | MAS1 (0.85) | MAS1AGTR2 | |
| SCHEMBL3908044 | 0.79 | MAS1 (0.69) | MAS1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218623-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF EPIDERMOLYSIS BULLOSA | TARIX ORPHAN LLC (US) | 2017-12-21 | — | — | WO | disclosed |