Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732957 | 1.00 | GAA (0.67) | GAAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL19732951 | 1.00 | GAA (0.67) | GAAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL14413503 | 0.88 | GAA (0.64) | GAAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL15196535 | 0.88 | USP2 (0.73) | GAAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL19732920 | 0.88 | USP2 (0.63) | GAAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL19732919 | 0.88 | USP2 (0.63) | GAAMAPTMEN1KMT2AUSP2 | |
| SCHEMBL19732955 | 0.86 | USP2 (0.79) | MAPTMEN1KMT2AUSP2TDP1 | |
| SCHEMBL19732923 | 0.86 | USP2 (0.79) | MAPTMEN1KMT2AUSP2TDP1 | |
| SCHEMBL13789190 | 0.86 | USP2 (0.79) | MAPTMEN1KMT2AUSP2TDP1 | |
| SCHEMBL2569532 | 0.85 | USP2 (0.52) | GAAMAPTMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |