Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924723 | 1.00 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL23924472 | 0.82 | — | — | |
| SCHEMBL1774832 | 0.81 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL5549078 | 0.81 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL3450115 | 0.81 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL15319039 | 0.81 | SPHK1 (0.50) | SPHK1 | |
| SCHEMBL15319038 | 0.81 | SPHK1 (0.50) | SPHK1 | |
| SCHEMBL28516296 | 0.80 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL1776206 | 0.77 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL25255699 | 0.75 | SPHK1 (0.32) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834239-B1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | ENTASIS THERAPEUTICS LTD (GB) | 2017-12-27 | — | — | EP | disclosed |
| CN-104364254-B | Heterobicyclic compounds as beta-lactamase inhibitors | 恩塔西斯治疗有限公司 | 2017-02-22 | — | — | CN | disclosed |